DegronMD - Q16538(GPR162)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T506I	TCGA-AX-A06F	UCEC	TCGA	IDETPLPS	DEG_SCF_FBW7_1	509:516	Mutation blocking phosphorylation signal	0.6944
p.R502Q	TCGA-FD-A43X	BLCA	TCGA	IDETPLPS	DEG_SCF_FBW7_1	509:516	Mutation rewiring degron network	0.1389
p.T506N	SIDM00315	Glioblastoma	GDSC	IDETPLPS	DEG_SCF_FBW7_1	509:516	Mutation blocking phosphorylation signal	0.6944
p.T506N	YKG-1	central nervous system	COSMIC	IDETPLPS	DEG_SCF_FBW7_1	509:516	Mutation blocking phosphorylation signal	0.6944
p.E504D	SIDM00474	Ovarian Carcinoma	GDSC	IDETPLPS	DEG_SCF_FBW7_1	509:516	Mutation rewiring degron network	0.1944
p.E504D	OV-7	ovary	COSMIC	IDETPLPS	DEG_SCF_FBW7_1	509:516	Mutation rewiring degron network	0.1944
p.R526C	SIDM01700	Hodgkin's Lymphoma	GDSC	IDETPLPS	DEG_SCF_FBW7_1	509:516	Mutation rewiring degron network	0.0556
p.E503D	SUP-HD1	haematopoietic and lymphoid tissue	COSMIC	IDETPLPS	DEG_SCF_FBW7_1	509:516	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons