DegronMD - Q16560(SNRNP35)

SNRNP35

UniProt ID: Q16560

Entrez ID: 11066

Protein name: U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) (Protein HM-1) (U1 snRNP-binding protein homolog)

External links: UniprotKB HGNC RefSeq COSMIC

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GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R163W	TCGA-AJ-A3BH	UCEC	TCGA	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.0833
p.R163W	TCGA-OR-A5J5	ACC	TCGA	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.0833
p.D179N	TCGA-AX-A1CE	UCEC	TCGA	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.3056
p.D179N	TCGA-AZ-6607	COAD	TCGA	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.3056
p.R168Q	TCGA-B5-A11E	UCEC	TCGA	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.2222
p.R168Q	TCGA-CA-6718	COAD	TCGA	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.2222
p.R188M	TCGA-D1-A2G0	UCEC	TCGA	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.0556
p.R186Q	TCGA-DJ-A1QH	THCA	TCGA	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.1111
p.R186Q	DO22237	LGG	ICGC	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.1111
p.R186Q	DO41572	UCEC	ICGC	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.1111
p.L173M	TCGA-ER-A1A1	SKCM	TCGA	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation altering degron motif	0.711
p.R163Q	DO7801	COAD	ICGC	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.0833
p.R163Q	DO41644	UCEC	ICGC	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.0833
p.D174N	DO8522	COAD	ICGC	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation altering degron motif	0.5821
p.D174N	DO42280	UCEC	ICGC	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation altering degron motif	0.5821
p.L168M	DO37413	SKCM	ICGC	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.2222
p.R181Q	DO39000	THCA	ICGC	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.25
p.R183M	DO43049	UCEC	ICGC	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation rewiring degron network	0.1944
p.E178G	ACH-001164	Sarcoma	CCLE	KNDLYRE	LIG_APCC_ABBAyCdc20_2	172:178	Mutation altering degron motif	0.7199

Kaplan plot for SNRNP35 in

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*NOTE: the Kaplan plots were collected from OncoLnc