DegronMD - Q16623(STX1A)

STX1A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D81N	TCGA-E6-A1LX	UCEC	TCGA	VRSKLKSIE	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.1111
p.D81N	DO41020	UCEC	ICGC	VRSKLKSIE	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.1111
p.M79K	DO224664	COCA	ICGC	VRSKLKSIE	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.0556
p.S99F	DO233867	GACA	ICGC	VRSKLKSIE	DEG_APCC_DBOX_1	89:97	Mutation blocking phosphorylation signal	0.7222
p.S95R	DO229029	LICA	ICGC	VRSKLKSIE	DEG_APCC_DBOX_1	89:97	Mutation altering degron motif	0.6316
p.E101D	DO50940	LICA	ICGC	VRSKLKSIE	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.2222
p.E103D	SIDM00217	Colorectal Carcinoma	GDSC	VRSKLKSIE	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.1667
p.E103D	ACH-000999	Colon/Colorectal Cancer	CCLE	VRSKLKSIE	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.1667
p.E103D	SNU-1040	large intestine	COSMIC	VRSKLKSIE	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc