DegronMD - Q16633(POU2AF1)

POU2AF1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A39T	TCGA-B5-A3FC	UCEC	TCGA	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.1389
p.A39T	DO41871	UCEC	ICGC	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.1389
p.A49V	TCGA-OR-A5J5	ACC	TCGA	APTAVVLPH	DEG_SIAH_1	46:54	Mutation altering degron motif	0.6936
p.A58V	DO8264	COAD	ICGC	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.2222
p.A58V	DO231941	LICA	ICGC	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.2222
p.A58E	DO229018	LICA	ICGC	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.2222
p.R36Q	SIDM00373	Endometrial Carcinoma	GDSC	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.0556
p.R36Q	ACH-000974	Endometrial/Uterine Cancer	CCLE	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.0556
p.T61A	SIDM00210	Ovarian Carcinoma	GDSC	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.1389
p.T61A	SIDM00703	Non-Small Cell Lung Carcinoma	GDSC	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.1389
p.T61A	SIDM00971	Breast Carcinoma	GDSC	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.1389
p.T61A	SIDM00254	Neuroblastoma	GDSC	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.1389
p.T61A	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.1389
p.T61A	SIDM01605	Non-Small Cell Lung Carcinoma	GDSC	APTAVVLPH	DEG_SIAH_1	46:54	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc