PWWP3A
UniProt ID: Q2TAK8
Entrez ID: 84939
Protein name: PWWP domain-containing DNA repair factor 3A (PWWP3A) (Mutated melanoma-associated antigen 1) (MUM-1) (PWWP domain-containing protein MUM1) (Protein expandere)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient...
FUNCTION: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. {ECO:0000269|PubMed:20347427}.
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GO - Biological processes (BP):
chromatin organization [GO:0006325]; DNA repair [GO:0006281]...
chromatin organization [GO:0006325]; DNA repair [GO:0006281]
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GO - Molecular function (MF):
nucleosome binding [GO:0031491]...
nucleosome binding [GO:0031491]
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GO - Cellular component (CC):
cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]...
cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]
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PWWP3A
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Kaplan plot for PWWP3A in
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*NOTE: the Kaplan plots were collected from OncoLnc