DegronMD - Q2TAL8(QRICH1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P86L	TCGA-AZ-6601	COAD	TCGA	PVTTS	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.25
p.P86L	DO8119	COAD	ICGC	PVTTS	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.25
p.K353T	TCGA-EO-A3B0	UCEC	TCGA	VGTTS	DEG_SPOP_SBC_1	362:366	Mutation substituting flanking lysine	0.1944
p.K353T	DO219773	UCEC	ICGC	VGTTS	DEG_SPOP_SBC_1	362:366	Mutation substituting flanking lysine	0.1944
p.T88A	TCGA-EY-A1GW	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.1944
p.T88A	DO42536	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.1944
p.K369E	DO222884	COCA	ICGC	VGTTS	DEG_SPOP_SBC_1	362:366	Mutation substituting flanking lysine	0.3611
p.T88N	DO228952	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.1944
p.T88N	DO229029	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.1944
p.Q92K	DO229031	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.0833
p.Q92K	DO229035	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.0833
p.Q90L	DO229275	THCA	ICGC	PVTTS	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons