DegronMD - Q2TAM9(TUSC1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E178K	TCGA-J1-A4AH	LUSC	TCGA	LQLHLE	LIG_APCC_ABBA_1	173:178	Mutation altering degron motif	0.7022
p.E178K	DO45479	LUSC	ICGC	LQLHLE	LIG_APCC_ABBA_1	173:178	Mutation altering degron motif	0.7022
p.E178Q	TCGA-JW-A5VL	CESC	TCGA	LQLHLE	LIG_APCC_ABBA_1	173:178	Mutation altering degron motif	0.6744
p.E178Q	DO49976	CESC	ICGC	LQLHLE	LIG_APCC_ABBA_1	173:178	Mutation altering degron motif	0.6744
p.R170Q	ACH-000958	Colon/Colorectal Cancer	CCLE	LQLHLE	LIG_APCC_ABBA_1	173:178	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons