DegronMD - Q2TAP0(GOLGA7B)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E133Q	TCGA-IR-A3LK	CESC	TCGA	ISIYED	LIG_APCC_ABBA_1	134:139	Mutation rewiring degron network	0.3056
p.E133Q	DO44299	CESC	ICGC	ISIYED	LIG_APCC_ABBA_1	134:139	Mutation rewiring degron network	0.3056
p.R140Q	DO233619	GACA	ICGC	ISIYED	LIG_APCC_ABBA_1	134:139	Mutation rewiring degron network	0.3056
p.E138D	DO229019	LICA	ICGC	ISIYED	LIG_APCC_ABBA_1	134:139	Mutation altering degron motif	0.5647
p.L128I	DO52667	MALY	ICGC	ISIYED	LIG_APCC_ABBA_1	134:139	Mutation rewiring degron network	0.1667
p.I136V	ACH-000962	Ovarian Cancer	CCLE	ISIYED	LIG_APCC_ABBA_1	134:139	Mutation altering degron motif	0.5965
p.I136V	ACH-001145	Ovarian Cancer	CCLE	ISIYED	LIG_APCC_ABBA_1	134:139	Mutation altering degron motif	0.5965
p.I136V	OC-314	ovary	COSMIC	ISIYED	LIG_APCC_ABBA_1	134:139	Mutation altering degron motif	0.5965
p.G144D	ACH-000989	Colon/Colorectal Cancer	CCLE	ISIYED	LIG_APCC_ABBA_1	134:139	Mutation rewiring degron network	0.1944
p.I135V	OC-314	ovary	COSMIC	ISIYED	LIG_APCC_ABBA_1	134:139	Mutation altering degron motif	0.7076

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons