DegronMD - Q32NC0(C18orf21)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q200K	TCGA-09-2044	OV	TCGA	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation rewiring degron network	0.1389
p.Q200K	DO28923	OV	ICGC	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation rewiring degron network	0.1389
p.D206N	TCGA-AP-A1DK	UCEC	TCGA	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation rewiring degron network	0.3056
p.D206N	DO42033	UCEC	ICGC	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation rewiring degron network	0.3056
p.L218V	TCGA-B1-A47M	KIRP	TCGA	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation rewiring degron network	0.25
p.L218V	DO49736	KIRP	ICGC	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation rewiring degron network	0.25
p.K201N	TCGA-D1-A103	UCEC	TCGA	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation substituting flanking lysine	0.2778
p.K201N	DO42312	UCEC	ICGC	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation substituting flanking lysine	0.2778
p.F210Y	TCGA-D1-A17Q	UCEC	TCGA	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation altering degron motif	0.6417
p.F210Y	DO41903	UCEC	ICGC	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation altering degron motif	0.6417
p.N209T	TCGA-F5-6814	READ	TCGA	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation altering degron motif	0.5944
p.N209T	DO36556	READ	ICGC	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation altering degron motif	0.5944
p.S213P	TCGA-FS-A1Z3	SKCM	TCGA	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation altering degron motif	0.6752
p.S213P	DO37635	SKCM	ICGC	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation altering degron motif	0.6752
p.F210V	DO222798	COCA	ICGC	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation altering degron motif	0.5957
p.R208G	DO222644	MELA	ICGC	FRNFLSSLK	DEG_APCC_DBOX_1	207:215	Mutation altering degron motif	0.7568

Kaplan plot for C18orf21 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

C18orf21

UniProt ID: Q32NC0

Entrez ID: 83608

Protein name: UPF0711 protein C18orf21 (HBV X-transactivated gene 13 protein) (HBV XAg-transactivated protein 13)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for C18orf21 in