DegronMD - Q32P44(EML3)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S874L	DO44373	CESC	ICGC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation rewiring degron network	0.1944
p.H887N	DO228974	LICA	ICGC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation blocking phosphorylation signal	0.7222
p.H887N	DO229025	LICA	ICGC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation blocking phosphorylation signal	0.7222
p.N882K	DO47542	SKCM	ICGC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation altering degron motif	0.6918
p.P876L	SIDM00520	Mesothelioma	GDSC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation rewiring degron network	0.25
p.P876L	SIDM01037	Breast Carcinoma	GDSC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation rewiring degron network	0.25
p.G894V	SIDM01100	Neuroblastoma	GDSC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation rewiring degron network	0.0833
p.G894V	SK-N-DZ	autonomic ganglia	COSMIC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation rewiring degron network	0.0833
p.P886L	ACH-000968	Skin Cancer	CCLE	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation rewiring degron network	0.3056
p.P886L	COLO-792	skin	COSMIC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation rewiring degron network	0.3056
p.P886S	ACH-000968	Skin Cancer	CCLE	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation rewiring degron network	0.3056
p.P886S	COLO-792	skin	COSMIC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation rewiring degron network	0.3056
p.C878R	22RV1	prostate	COSMIC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation rewiring degron network	0.3056
p.A884T	UWB1_289	ovary	COSMIC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation altering degron motif	0.7139
p.P887S	COLO-792	skin	COSMIC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation blocking phosphorylation signal	0.7222
p.P887L	COLO-792	skin	COSMIC	PATPSRT	DEG_SCF_FBW7_1	879:885	Mutation blocking phosphorylation signal	0.7222

Kaplan plot for EML3 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

EML3

UniProt ID: Q32P44

Entrez ID: 256364

Protein name: Echinoderm microtubule-associated protein-like 3 (EMAP-3)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for EML3 in