DegronMD - Q3LI83(KRTAP24-1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.C24S	TCGA-56-8626	LUSC	TCGA	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.25
p.C24S	DO45506	LUSC	ICGC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.25
p.T17S	TCGA-69-7979	LUAD	TCGA	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.0556
p.T17S	DO23874	LUAD	ICGC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.0556
p.R21I	TCGA-AG-3892	READ	TCGA	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.1667
p.R21I	DO36394	READ	ICGC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.1667
p.S31Y	TCGA-AN-A046	BRCA	TCGA	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation altering degron motif	0.712
p.S31Y	TCGA-EO-A3B0	UCEC	TCGA	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation altering degron motif	0.712
p.S31Y	DO1285	BRCA	ICGC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation altering degron motif	0.712
p.S31Y	DO219773	UCEC	ICGC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation altering degron motif	0.712
p.T17I	TCGA-BH-A0DG	BRCA	TCGA	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.0556
p.T17I	DO1257	BRCA	ICGC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.0556
p.V28L	DO50439	ESAD	ICGC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation altering degron motif	0.5654
p.S36P	DO234258	ESAD	ICGC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.1944
p.R21S	DO231598	LINC	ICGC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.1667
p.R21S	DO231553	LINC	ICGC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.1667
p.S30P	DO229237	LMS	ICGC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation altering degron motif	0.6752
p.S35G	SIDM01146	Gastric Carcinoma	GDSC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.2222
p.S35G	ACH-000932	Gastric Cancer	CCLE	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.2222
p.S35G	NCI-SNU-1	stomach	COSMIC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.2222
p.C24W	SIDM00118	Colorectal Carcinoma	GDSC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.25
p.C24W	ACH-001081	Colon/Colorectal Cancer	CCLE	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.25
p.C24W	HCC2998	large intestine	COSMIC	PVTSS	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.25

Kaplan plot for KRTAP24-1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

KRTAP24-1

UniProt ID: Q3LI83

Entrez ID: 643803

Protein name: Keratin-associated protein 24-1

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for KRTAP24-1 in