DegronMD - Q3LXA3(TKFC)

TKFC

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A488V	SIDM00781	Colorectal Carcinoma	GDSC	DRTMLDSLW	DEG_APCC_DBOX_1	492:500	Mutation rewiring degron network	0.2222
p.A488V	SIDM00780	Colorectal Carcinoma	GDSC	DRTMLDSLW	DEG_APCC_DBOX_1	492:500	Mutation rewiring degron network	0.2222
p.A488V	SNU-C2B	large intestine	COSMIC	DRTMLDSLW	DEG_APCC_DBOX_1	492:500	Mutation rewiring degron network	0.2222
p.A502V	SIDM00673	Breast Carcinoma	GDSC	DRTMLDSLW	DEG_APCC_DBOX_1	492:500	Mutation rewiring degron network	0.2778
p.A502V	HCC70	breast	COSMIC	DRTMLDSLW	DEG_APCC_DBOX_1	492:500	Mutation rewiring degron network	0.2778
p.R493G	SIDM01727	Chronic Myelogenous Leukemia	GDSC	DRTMLDSLW	DEG_APCC_DBOX_1	492:500	Mutation altering degron motif	0.7568
p.R493G	SIDM00173	Head and Neck Carcinoma	GDSC	DRTMLDSLW	DEG_APCC_DBOX_1	492:500	Mutation altering degron motif	0.7568

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*NOTE: the Kaplan plots were collected from OncoLnc