DegronMD - Q3MIW9(MUCL3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A397V	SIDM00544	Neuroblastoma	GDSC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation rewiring degron network	0.1389
p.A397V	GOTO	autonomic ganglia	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation rewiring degron network	0.1389
p.A409T	SIDM01169	Ovarian Carcinoma	GDSC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation altering degron motif	0.7139
p.A409T	SIDM00557	Neuroblastoma	GDSC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation altering degron motif	0.7139
p.A409T	TOV-21G	ovary	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation altering degron motif	0.7139
p.A409T	KP-N-RT-BM-1	autonomic ganglia	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation altering degron motif	0.7139
p.K412N	SIDM00557	Neuroblastoma	GDSC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation altering degron motif	0.6918
p.K412N	KP-N-RT-BM-1	autonomic ganglia	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation altering degron motif	0.6918
p.E419D	SIDM00730	Small Cell Lung Carcinoma	GDSC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation rewiring degron network	0.1389
p.E419D	NCI-H2227	lung	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation rewiring degron network	0.1389
p.R413K	NB14	autonomic ganglia	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation rewiring degron network	0.3056
p.A407V	KCL-22	haematopoietic and lymphoid tissue	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation altering degron motif	0.6936
p.A407V	KP-2	pancreas	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation altering degron motif	0.6936
p.A407V	SBC-3	lung	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation altering degron motif	0.6936
p.S398F	KYSE-220	oesophagus	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation rewiring degron network	0.1667
p.T403A	SNU-1040	large intestine	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation rewiring degron network	0.3056
p.A403T	NALM-6	haematopoietic and lymphoid tissue	COSMIC	SRTKLSSIT	DEG_APCC_DBOX_1	404:412	Mutation rewiring degron network	0.3056

Kaplan plot for MUCL3 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MUCL3

UniProt ID: Q3MIW9

Entrez ID: 135656

Protein name: Mucin-like protein 3 (Diffuse panbronchiolitis critical region protein 1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MUCL3 in