DegronMD - Q3MJ16(PLA2G4E)

PLA2G4E

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A828T	TCGA-49-AARE	LUAD	TCGA	PKTPYAT	DEG_SCF_FBW7_1	814:820	Mutation rewiring degron network	0.1111
p.A828T	DO218922	LUAD	ICGC	PKTPYAT	DEG_SCF_FBW7_1	814:820	Mutation rewiring degron network	0.1111
p.D810G	TCGA-AP-A1DV	UCEC	TCGA	PKTPYAT	DEG_SCF_FBW7_1	814:820	Mutation rewiring degron network	0.2222
p.D810G	DO43186	UCEC	ICGC	PKTPYAT	DEG_SCF_FBW7_1	814:820	Mutation rewiring degron network	0.2222
p.E822K	TCGA-D9-A6EC	SKCM	TCGA	PKTPYAT	DEG_SCF_FBW7_1	814:820	Mutation rewiring degron network	0.2778
p.E822K	DO50291	SKCM	ICGC	PKTPYAT	DEG_SCF_FBW7_1	814:820	Mutation rewiring degron network	0.2778
p.E805K	TCGA-ER-A194	SKCM	TCGA	PKTPYAT	DEG_SCF_FBW7_1	814:820	Mutation rewiring degron network	0.0833
p.E805K	DO47646	SKCM	ICGC	PKTPYAT	DEG_SCF_FBW7_1	814:820	Mutation rewiring degron network	0.0833
p.Q806L	DO49667	LIAD	ICGC	PKTPYAT	DEG_SCF_FBW7_1	814:820	Mutation rewiring degron network	0.1111
p.Q808R	DO49667	LIAD	ICGC	PKTPYAT	DEG_SCF_FBW7_1	814:820	Mutation rewiring degron network	0.1667
p.P814H	DO229027	LICA	ICGC	PKTPYAT	DEG_SCF_FBW7_1	814:820	Mutation altering degron motif	0.7694

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*NOTE: the Kaplan plots were collected from OncoLnc