DegronMD - Q3YBR2(TBRG1)

TBRG1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L150M	TCGA-AP-A051	UCEC	TCGA	GKENN	DEG_APCC_KENBOX_2	144:148	Mutation rewiring degron network	0.2778
p.L150M	DO42673	UCEC	ICGC	GKENN	DEG_APCC_KENBOX_2	144:148	Mutation rewiring degron network	0.2778
p.K145N	TCGA-DF-A2KN	UCEC	TCGA	GKENN	DEG_APCC_KENBOX_2	144:148	Mutation altering degron motif	0.6918
p.K145N	DO223282	UCEC	ICGC	GKENN	DEG_APCC_KENBOX_2	144:148	Mutation altering degron motif	0.6918
p.C157R	TCGA-JX-A3Q8	CESC	TCGA	GKENN	DEG_APCC_KENBOX_2	144:148	Mutation rewiring degron network	0.0833
p.C157R	DO51608	CESC	ICGC	GKENN	DEG_APCC_KENBOX_2	144:148	Mutation rewiring degron network	0.0833
p.K140R	DO230334	COCA	ICGC	GKENN	DEG_APCC_KENBOX_2	144:148	Mutation substituting flanking lysine	0.3333
p.C157S	ACH-000037	Sarcoma	CCLE	GKENN	DEG_APCC_KENBOX_2	144:148	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc