DegronMD - Q3ZCT1(ZNF260)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G216R	TCGA-95-7043	LUAD	TCGA	QKENL	DEG_APCC_KENBOX_2	203:207	Mutation rewiring degron network	0.0833
p.G216R	DO24739	LUAD	ICGC	QKENL	DEG_APCC_KENBOX_2	203:207	Mutation rewiring degron network	0.0833
p.H210Y	DO233782	GACA	ICGC	QKENL	DEG_APCC_KENBOX_2	203:207	Mutation rewiring degron network	0.25
p.E196K	DO220906	MELA	ICGC	QKENL	DEG_APCC_KENBOX_2	203:207	Mutation rewiring degron network	0.1389
p.S195G	SIDM00661	B-Cell Non-Hodgkin's Lymphoma	GDSC	QKENL	DEG_APCC_KENBOX_2	203:207	Mutation rewiring degron network	0.1111
p.S195G	ACH-000914	Lymphoma	CCLE	QKENL	DEG_APCC_KENBOX_2	203:207	Mutation rewiring degron network	0.1111
p.S195G	HT	haematopoietic and lymphoid tissue	COSMIC	QKENL	DEG_APCC_KENBOX_2	203:207	Mutation rewiring degron network	0.1111
p.G198E	SIDM01368	Gastric Carcinoma	GDSC	QKENL	DEG_APCC_KENBOX_2	203:207	Mutation rewiring degron network	0.1944
p.G198E	ACH-000255	Gastric Cancer	CCLE	QKENL	DEG_APCC_KENBOX_2	203:207	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons