DegronMD - Q4G176(ACSF3)

ACSF3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D408Y	TCGA-50-5930	LUAD	TCGA	VTPGFE	DEG_SCF_FBW7_2	414:419	Mutation rewiring degron network	0.1667
p.D408Y	DO25189	LUAD	ICGC	VTPGFE	DEG_SCF_FBW7_2	414:419	Mutation rewiring degron network	0.1667
p.F418L	TCGA-AB-2913	LAML	TCGA	VTPGFE	DEG_SCF_FBW7_2	414:419	Mutation altering degron motif	0.587
p.F418L	DO21493	LAML	ICGC	VTPGFE	DEG_SCF_FBW7_2	414:419	Mutation altering degron motif	0.587
p.E409K	TCGA-EE-A3AE	SKCM	TCGA	VTPGFE	DEG_SCF_FBW7_2	414:419	Mutation rewiring degron network	0.1944
p.E409K	DO37802	SKCM	ICGC	VTPGFE	DEG_SCF_FBW7_2	414:419	Mutation rewiring degron network	0.1944
p.P416S	DO222526	ESCA	ICGC	VTPGFE	DEG_SCF_FBW7_2	414:419	Mutation altering degron motif	0.6752
p.R428M	DO46342	OV	ICGC	VTPGFE	DEG_SCF_FBW7_2	414:419	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc