DegronMD - Q4KMQ2(ANO6)

ANO6

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G21V	TCGA-D3-A2J8	SKCM	TCGA	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation rewiring degron network	0.1111
p.G21V	DO37778	SKCM	ICGC	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation rewiring degron network	0.1111
p.E16D	TCGA-VS-A9UZ	CESC	TCGA	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation rewiring degron network	0.25
p.E16D	DO51646	CESC	ICGC	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation rewiring degron network	0.25
p.N7I	DO222608	BTCA	ICGC	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation altering degron motif	0.6169
p.E22K	DO8890	COAD	ICGC	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation rewiring degron network	0.0833
p.S5N	SIDM00625	Other Sarcomas	GDSC	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation altering degron motif	0.5958
p.S5N	ACH-000449	Sarcoma	CCLE	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation altering degron motif	0.5958
p.S5N	MES-SA	soft tissue	COSMIC	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation altering degron motif	0.5958
p.M12I	ACH-000979	Prostate Cancer	CCLE	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation altering degron motif	0.6507
p.S23C	GP5d	large intestine	COSMIC	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation rewiring degron network	0.0556
p.N9S	EN	endometrium	COSMIC	SRNVLLQME	DEG_APCC_DBOX_1	5:13	Mutation altering degron motif	0.7069

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*NOTE: the Kaplan plots were collected from OncoLnc