DegronMD - Q52LJ0(FAM98B)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T156A	TCGA-34-5241	LUSC	TCGA	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.2222
p.T156A	DO27341	LUSC	ICGC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.2222
p.F154C	TCGA-A5-A2K5	UCEC	TCGA	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.1667
p.F154C	DO41379	UCEC	ICGC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.1667
p.P160H	TCGA-D3-A2JP	SKCM	TCGA	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation altering degron motif	0.7694
p.P160H	DO47407	SKCM	ICGC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation altering degron motif	0.7694
p.Q173K	TCGA-ET-A39J	THCA	TCGA	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.0833
p.Q173K	DO38956	THCA	ICGC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.0833
p.P168L	DO233905	GACA	ICGC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.2222
p.M153I	DO229032	LICA	ICGC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.1389
p.H169Y	DO230525	LUSC	ICGC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.1944
p.I159T	DO229253	THCA	ICGC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.3056
p.D155H	SIDM01015	Chronic Myelogenous Leukemia	GDSC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.1944
p.D155H	ACH-000326	Leukemia	CCLE	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.1944
p.D155H	JURL-MK1	haematopoietic and lymphoid tissue	COSMIC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.1944
p.T156I	SIDM00332	Breast Carcinoma	GDSC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.2222
p.T156I	ACH-001819	Breast Cancer	CCLE	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.2222
p.T156I	MFM-223	breast	COSMIC	PKSTT	DEG_SPOP_SBC_1	160:164	Mutation rewiring degron network	0.2222

Kaplan plot for FAM98B in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FAM98B

UniProt ID: Q52LJ0

Entrez ID: 283742

Protein name: Protein FAM98B

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for FAM98B in