DegronMD - Q53H96(PYCR3)

PYCR3

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R243H	SIDM00217	Colorectal Carcinoma	GDSC	VCTPGGT	DEG_SCF_FBW7_1	234:240	Mutation rewiring degron network	0.25
p.R243H	SNU-1040	large intestine	COSMIC	VCTPGGT	DEG_SCF_FBW7_1	234:240	Mutation rewiring degron network	0.25
p.G236C	SIDM01608	Endometrial Carcinoma	GDSC	VCTPGGT	DEG_SCF_FBW7_1	234:240	Mutation altering degron motif	0.76
p.A240T	C-33-A	cervix	COSMIC	VCTPGGT	DEG_SCF_FBW7_1	234:240	Mutation altering degron motif	0.7139
p.R231H	SNU-1040	large intestine	COSMIC	VCTPGGT	DEG_SCF_FBW7_1	234:240	Mutation rewiring degron network	0.25
p.E249Q	BT-483	breast	COSMIC	VCTPGGT	DEG_SCF_FBW7_1	234:240	Mutation rewiring degron network	0.0833
p.E229Q	BT-483	breast	COSMIC	VCTPGGT	DEG_SCF_FBW7_1	234:240	Mutation rewiring degron network	0.1944
p.R234Q	SNU-407	large intestine	COSMIC	VCTPGGT	DEG_SCF_FBW7_1	234:240	Mutation altering degron motif	0.7329
p.L233M	AM-38	central nervous system	COSMIC	VCTPGGT	DEG_SCF_FBW7_1	234:240	Mutation rewiring degron network	0.3056

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc