DegronMD - Q569G3(C5orf47)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q92E	DO225140	BRCA	ICGC	VPTTPGVE	DEG_SCF_FBW7_2	77:84	Mutation rewiring degron network	0.1111
p.R76K	DO228870	LICA	ICGC	VPTTPGVE	DEG_SCF_FBW7_2	77:84	Mutation rewiring degron network	0.3056
p.S73F	DO222395	MELA	ICGC	VPTTPGVE	DEG_SCF_FBW7_2	77:84	Mutation rewiring degron network	0.2222
p.Q74K	DO229253	THCA	ICGC	VPTTPGVE	DEG_SCF_FBW7_2	77:84	Mutation rewiring degron network	0.25
p.S67N	DO43763	UCEC	ICGC	VPTTPGVE	DEG_SCF_FBW7_2	77:84	Mutation rewiring degron network	0.0556
p.S88Y	ACH-001515	Cervical Cancer	CCLE	VPTTPGVE	DEG_SCF_FBW7_2	77:84	Mutation blocking phosphorylation signal	0.6667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons