DegronMD

Uniprot ID: Q569G3

Source protein: Uncharacterized protein C5orf47

Source gene: C5orf47

Class: DEG_SCF_FBW7_2

Location: 77:84

E3 ligase: FBXW7

DEGRON score: 0.9976

ASA_SCORE: 78.425

COIL: 0.8451

CONS_SCORE: 0.4799

DSS_SCORE: 0.5253

HELIX: 0.1114

FCONS_SCORE: 0.8908

RIG_SCORE: 0.7007

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.Q92E	DO225140	BRCA	ICGC	VPTTPGVE	DEG_SCF_FBW7_2	0.1111
p.R76K	DO228870	LICA	ICGC	VPTTPGVE	DEG_SCF_FBW7_2	0.3056
p.S73F	DO222395	MELA	ICGC	VPTTPGVE	DEG_SCF_FBW7_2	0.2222
p.Q74K	DO229253	THCA	ICGC	VPTTPGVE	DEG_SCF_FBW7_2	0.25
p.S67N	DO43763	UCEC	ICGC	VPTTPGVE	DEG_SCF_FBW7_2	0.0556
p.S88Y	ACH-001515	Cervical Cancer	CCLE	VPTTPGVE	DEG_SCF_FBW7_2	0.6667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q569G3	Uncharacterized protein C5orf47	DEG_SCF_FBW7_2	77:84	VPTTPGVE	FBXW7	0.9976	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons