DegronMD - Q5FWF4(ZRANB3)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S607I	TCGA-37-4135	LUSC	TCGA	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.3056
p.S607I	DO26806	LUSC	ICGC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.3056
p.S657N	TCGA-AP-A1E0	UCEC	TCGA	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.1389
p.S657N	DO43154	UCEC	ICGC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.1389
p.E591Q	TCGA-B6-A0RE	BRCA	TCGA	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.0833
p.E591Q	DO3482	BRCA	ICGC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.0833
p.T616I	TCGA-D3-A8GC	SKCM	TCGA	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.0556
p.T616I	DO50281	SKCM	ICGC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.0556
p.P639T	TCGA-L3-A524	LUSC	TCGA	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.2222
p.P639T	DO45476	LUSC	ICGC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.2222
p.T593R	TCGA-OR-A5JE	ACC	TCGA	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.1389
p.P594S	TCGA-XK-AAIW	PRAD	TCGA	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.1667
p.P594S	DO51407	PRAD	ICGC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.1667
p.E637V	DO229010	COCA	ICGC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.1667
p.E637V	DO229013	COCA	ICGC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.1667
p.E637V	DO229016	COCA	ICGC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.1667
p.E637V	DO229480	LAML	ICGC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.1667
p.E637V	DO52365	LUSC	ICGC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.1667
p.E637V	DO218852	SKCA	ICGC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.1667
p.R601Q	DO229016	COCA	ICGC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	DO229505	LAML	ICGC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00557	Neuroblastoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00973	Melanoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00689	B-Lymphoblastic Leukemia	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00578	Neuroblastoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00450	Acute Myeloid Leukemia	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00586	Hepatocellular Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01020	Plasma Cell Myeloma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00987	Thyroid Gland Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00297	Non-Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01040	Ovarian Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01197	Colorectal Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00723	Non-Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00938	Breast Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01248	Thyroid Gland Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00602	Gastric Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01199	Hepatocellular Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01219	Non-Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00981	B-Cell Non-Hodgkin's Lymphoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00919	Ovarian Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00718	Non-Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00446	Acute Myeloid Leukemia	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00369	Esophageal Squamous Cell Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00315	Glioblastoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00860	Head and Neck Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01092	B-Cell Non-Hodgkin's Lymphoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01144	Gastric Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00057	Neuroblastoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00481	Ovarian Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00589	Oral Cavity Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00552	Rhabdomyosarcoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00474	Ovarian Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00472	Ovarian Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00598	Squamous Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00394	Cervical Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00356	Non-Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00942	Oral Cavity Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00350	Head and Neck Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00966	Ovarian Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00098	Mesothelioma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00095	Glioblastoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00260	Gastric Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00538	Esophageal Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01196	Hepatocellular Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00351	Oral Cavity Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00223	Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00486	Squamous Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00487	Colorectal Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00294	Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00939	Non-Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01146	Gastric Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00247	Gastric Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00612	Glioma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01182	Bladder Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00462	Acute Myeloid Leukemia	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00576	Acute Myeloid Leukemia	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00400	B-Cell Non-Hodgkin's Lymphoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00970	Bladder Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00616	Hepatocellular Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01187	Breast Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00685	Glioblastoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00566	Oral Cavity Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00241	Breast Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00724	Non-Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01257	Hepatocellular Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00380	Acute Myeloid Leukemia	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01067	Non-Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00996	Thyroid Gland Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01170	Ovarian Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00554	Ovarian Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00349	Esophageal Squamous Cell Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01695	Acute Myeloid Leukemia	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01551	Gastric Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00165	Other Solid Cancers	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01449	Pancreatic Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01780	B-Cell Non-Hodgkin's Lymphoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01504	Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01770	Gastric Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00062	Hepatocellular Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00160	Biliary Tract Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01758	B-Cell Non-Hodgkin's Lymphoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01469	Pancreatic Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00248	Gastric Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01167	Thyroid Gland Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01494	Glioblastoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01445	Gastric Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01433	Kidney Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00959	Acute Myeloid Leukemia	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01491	Colorectal Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM01566	Hodgkin's Lymphoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.R601Q	SIDM00171	Colorectal Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6218
p.T646A	DO231072	LUSC	ICGC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation altering degron motif	0.7139
p.T646A	SIDM00290	Gastric Carcinoma	GDSC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation altering degron motif	0.7139
p.T646A	SIDM00164	Biliary Tract Carcinoma	GDSC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation altering degron motif	0.7139
p.T646A	SIDM01473	Plasma Cell Myeloma	GDSC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation altering degron motif	0.7139
p.K612T	SIDM01291	Esophageal Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation substituting flanking lysine	0.2778
p.V605M	SIDM00672	Hepatocellular Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM01104	Melanoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00773	Non-Cancerous	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM01090	Colorectal Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM01117	Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00659	Glioblastoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00656	Burkitt's Lymphoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00447	B-Lymphoblastic Leukemia	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00797	Melanoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00694	Other Solid Cancers	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00948	Burkitt's Lymphoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00254	Neuroblastoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00844	Burkitt's Lymphoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00032	Bladder Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00431	T-Lymphoblastic Leukemia	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00774	Breast Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00720	Mesothelioma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00760	Small Cell Lung Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM01173	Rhabdomyosarcoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM00641	Burkitt's Lymphoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM01686	Chronic Myelogenous Leukemia	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.V605M	SIDM01664	Prostate Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.6097
p.I633F	SIDM00483	Esophageal Carcinoma	GDSC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.0556
p.I633F	ACH-001654	Esophageal Cancer	CCLE	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.0556
p.I633F	SK-GT-4	oesophagus	COSMIC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.0556
p.L604F	SIDM01066	Melanoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.587
p.L604F	ACH-000650	Skin Cancer	CCLE	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.587
p.L604F	IGR-37	skin	COSMIC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.587
p.S607R	SIDM00665	Gastric Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.3056
p.S607R	ACH-000616	Gastric Cancer	CCLE	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.3056
p.S607R	Hs746T	stomach	COSMIC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.3056
p.N659S	SIDM00068	Colorectal Carcinoma	GDSC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.0833
p.E592V	SIDM00954	Breast Carcinoma	GDSC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.1111
p.E592V	ACH-001820	Breast Cancer	CCLE	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.1111
p.E592V	COLO-824	breast	COSMIC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation rewiring degron network	0.1111
p.S650R	SIDM01768	Melanoma	GDSC	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation altering degron motif	0.7427
p.S650R	ACH-000899	Skin Cancer	CCLE	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation altering degron motif	0.7427
p.S636L	ACH-001396	Metastasis	CCLE	MCETPQGS	DEG_SCF_FBW7_1	643:650	Mutation rewiring degron network	0.1389
p.R602I	HT-115	large intestine	COSMIC	IRTPLVE	DEG_SCF_FBW7_2	600:606	Mutation altering degron motif	0.8102

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ZRANB3

UniProt ID: Q5FWF4

Entrez ID: 84083

Protein name: DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)]

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ZRANB3 in