DegronMD - Q5H9U9(DDX60L)

DDX60L

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V471A	TCGA-DI-A1BU	UCEC	TCGA	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.5825
p.V471A	DO42023	UCEC	ICGC	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.5825
p.P470S	TCGA-EE-A3J5	SKCM	TCGA	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.5641
p.P470S	DO47331	SKCM	ICGC	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.5641
p.P473L	TCGA-FR-A8YC	SKCM	TCGA	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.7582
p.P473L	DO50301	SKCM	ICGC	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.7582
p.P470L	DO222751	BTCA	ICGC	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.6471
p.L462S	DO50424	PRAD	ICGC	SDDPVVPSL	DEG_COP1_1	467:475	Mutation rewiring degron network	0.1944
p.D469N	SIDM00048	Non-Small Cell Lung Carcinoma	GDSC	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.5821
p.D469N	SIDM01318	Hepatocellular Carcinoma	GDSC	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.5821
p.D469N	SIDM01590	Breast Carcinoma	GDSC	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.5821
p.D469Y	SIDM00749	Non-Small Cell Lung Carcinoma	GDSC	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.6214
p.D469Y	NCI-H1573	lung	COSMIC	SDDPVVPSL	DEG_COP1_1	467:475	Mutation altering degron motif	0.6214

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*NOTE: the Kaplan plots were collected from OncoLnc