DegronMD - Q5JPI3(C3orf38)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V291A	TCGA-06-5416	GBM	TCGA	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.6936
p.V291A	DO10880	GBM	ICGC	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.6936
p.E294V	TCGA-55-A492	LUAD	TCGA	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation rewiring degron network	0.3056
p.E294V	DO44726	LICA	ICGC	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation rewiring degron network	0.3056
p.E294V	DO23708	LUAD	ICGC	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation rewiring degron network	0.3056
p.P289S	TCGA-D9-A6EC	SKCM	TCGA	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.5641
p.P289S	DO50291	SKCM	ICGC	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.5641
p.P289S	SIDM00759	Non-Small Cell Lung Carcinoma	GDSC	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.5641
p.P289S	SIDM00202	Ewing's Sarcoma	GDSC	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.5641
p.P289S	SIDM00327	Hodgkin's Lymphoma	GDSC	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.5641
p.P289L	TCGA-D9-A6EC	SKCM	TCGA	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.6471
p.P289L	DO50291	SKCM	ICGC	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.6471
p.L281I	TCGA-EE-A2GT	SKCM	TCGA	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.6063
p.L281I	DO37946	SKCM	ICGC	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.6063
p.S280F	TCGA-FS-A4F0	SKCM	TCGA	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation rewiring degron network	0.3056
p.S280F	DO37891	SKCM	ICGC	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation rewiring degron network	0.3056
p.P289A	SIDM00451	T-Lymphoblastic Leukemia	GDSC	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.6392
p.P289A	ACH-000937	Leukemia	CCLE	LAPGTLPKPSVKF	DEG_ODPH_VHL_1	281:293	Mutation altering degron motif	0.6392

Kaplan plot for C3orf38 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

C3orf38

UniProt ID: Q5JPI3

Entrez ID: 285237

Protein name: Uncharacterized protein C3orf38

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for C3orf38 in