DegronMD - Q5JR12(PPM1J)

PPM1J

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L213V	TCGA-AP-A056	UCEC	TCGA	PGTPDSS	DEG_SCF_FBW7_1	202:208	Mutation rewiring degron network	0.1944
p.L213V	DO43971	UCEC	ICGC	PGTPDSS	DEG_SCF_FBW7_1	202:208	Mutation rewiring degron network	0.1944
p.P202Q	DO222856	COCA	ICGC	PGTPDSS	DEG_SCF_FBW7_1	202:208	Mutation altering degron motif	0.7035
p.P202Q	SIDM02021	Esophageal Carcinoma	GDSC	PGTPDSS	DEG_SCF_FBW7_1	202:208	Mutation altering degron motif	0.7035
p.P193L	DO228585	LICA	ICGC	PGTPDSS	DEG_SCF_FBW7_1	202:208	Mutation rewiring degron network	0.0833
p.P202S	DO220881	MELA	ICGC	PGTPDSS	DEG_SCF_FBW7_1	202:208	Mutation altering degron motif	0.6752
p.S218P	SIDM01016	T-Lymphoblastic Leukemia	GDSC	PGTPDSS	DEG_SCF_FBW7_1	202:208	Mutation rewiring degron network	0.0556
p.S218P	SIDM01263	T-Lymphoblastic Leukemia	GDSC	PGTPDSS	DEG_SCF_FBW7_1	202:208	Mutation rewiring degron network	0.0556
p.S218P	ACH-000995	Leukemia	CCLE	PGTPDSS	DEG_SCF_FBW7_1	202:208	Mutation rewiring degron network	0.0556
p.S218P	Jurkat	haematopoietic and lymphoid tissue	COSMIC	PGTPDSS	DEG_SCF_FBW7_1	202:208	Mutation rewiring degron network	0.0556
p.P216H	ACH-001610	Brain Cancer	CCLE	PGTPDSS	DEG_SCF_FBW7_1	202:208	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc