DegronMD - Q5JVS0(HABP4)

HABP4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S265Y	TCGA-FS-A1ZJ	SKCM	TCGA	EEESPAKVPEL	DEG_COP1_1	270:280	Mutation rewiring degron network	0.1944
p.S265Y	DO37956	SKCM	ICGC	EEESPAKVPEL	DEG_COP1_1	270:280	Mutation rewiring degron network	0.1944
p.R264H	DO683	BLCA	ICGC	EEESPAKVPEL	DEG_COP1_1	270:280	Mutation rewiring degron network	0.1667
p.G272E	DO49950	CESC	ICGC	EEESPAKVPEL	DEG_COP1_1	270:280	Mutation altering degron motif	0.7199
p.G272E	NCI-H510A	lung	COSMIC	EEESPAKVPEL	DEG_COP1_1	270:280	Mutation altering degron motif	0.7199
p.E264D	DO229051	LICA	ICGC	EEESPAKVPEL	DEG_COP1_1	270:280	Mutation rewiring degron network	0.1667
p.P260H	LNCaP-Clone-FGC	prostate	COSMIC	EEESPAKVPEL	DEG_COP1_1	270:280	Mutation rewiring degron network	0.0556
p.R261C	HCC2998	large intestine	COSMIC	EEESPAKVPEL	DEG_COP1_1	270:280	Mutation rewiring degron network	0.0833
p.R274W	OSC-20	upper aerodigestive tract	COSMIC	EEESPAKVPEL	DEG_COP1_1	270:280	Mutation altering degron motif	0.8634
p.R274W	NOS-1	bone	COSMIC	EEESPAKVPEL	DEG_COP1_1	270:280	Mutation altering degron motif	0.8634
p.R271Q	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	EEESPAKVPEL	DEG_COP1_1	270:280	Mutation altering degron motif	0.7329

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*NOTE: the Kaplan plots were collected from OncoLnc