DegronMD - Q5JWR5(DOP1A)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.C901R	SIDM00119	Non-Small Cell Lung Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	904:908	Mutation rewiring degron network	0.25
p.C901R	EKVX	lung	COSMIC	VPSSS	DEG_SPOP_SBC_1	904:908	Mutation rewiring degron network	0.25
p.D1118Y	SIDM01128	Small Cell Lung Carcinoma	GDSC	DSGCSQS	DEG_SCF_TRCP1_1	1110:1116	Mutation rewiring degron network	0.2778
p.D1118Y	NCI-H526	lung	COSMIC	DSGCSQS	DEG_SCF_TRCP1_1	1110:1116	Mutation rewiring degron network	0.2778
p.C910R	EKVX	lung	COSMIC	VPSSS	DEG_SPOP_SBC_1	904:908	Mutation rewiring degron network	0.2778
p.I1105M	HEC-1	endometrium	COSMIC	DSGCSQS	DEG_SCF_TRCP1_1	1110:1116	Mutation rewiring degron network	0.1944
p.N902T	LU-165	lung	COSMIC	VPSSS	DEG_SPOP_SBC_1	904:908	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons