DegronMD - Q5MIZ7(PPP4R3B)

PPP4R3B

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T767S	SIDM01612	Endometrial Carcinoma	GDSC	DKENL	DEG_APCC_KENBOX_2	759:763	Mutation rewiring degron network	0.2222
p.N762Y	SIDM01435	Hepatocellular Carcinoma	GDSC	DKENL	DEG_APCC_KENBOX_2	759:763	Mutation altering degron motif	0.7059
p.R761L	CAL-78	bone	COSMIC	DKENL	DEG_APCC_KENBOX_2	759:763	Mutation altering degron motif	0.8428
p.S768F	CW-2	large intestine	COSMIC	DKENL	DEG_APCC_KENBOX_2	759:763	Mutation blocking phosphorylation signal	0.6389

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*NOTE: the Kaplan plots were collected from OncoLnc