DegronMD - Q5PRF9(SAMD4B)

SAMD4B

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V396I	TCGA-85-A4QR	LUSC	TCGA	AATTT	DEG_SPOP_SBC_1	403:407	Mutation rewiring degron network	0.1389
p.V396I	DO45523	LUSC	ICGC	AATTT	DEG_SPOP_SBC_1	403:407	Mutation rewiring degron network	0.1389
p.T405A	TCGA-AO-A128	BRCA	TCGA	AATTT	DEG_SPOP_SBC_1	403:407	Mutation altering degron motif	0.825
p.T405A	DO5326	BRCA	ICGC	AATTT	DEG_SPOP_SBC_1	403:407	Mutation altering degron motif	0.825
p.A404T	TCGA-CD-A4MI	STAD	TCGA	AATTT	DEG_SPOP_SBC_1	403:407	Mutation altering degron motif	0.6028
p.A404T	DO227731	COCA	ICGC	AATTT	DEG_SPOP_SBC_1	403:407	Mutation altering degron motif	0.6028
p.A404T	DO47717	STAD	ICGC	AATTT	DEG_SPOP_SBC_1	403:407	Mutation altering degron motif	0.6028
p.G416V	TCGA-G2-A2EJ	BLCA	TCGA	AATTT	DEG_SPOP_SBC_1	403:407	Mutation rewiring degron network	0.0833
p.G416V	DO554	BLCA	ICGC	AATTT	DEG_SPOP_SBC_1	403:407	Mutation rewiring degron network	0.0833
p.A410S	DO229019	LICA	ICGC	AATTT	DEG_SPOP_SBC_1	403:407	Mutation rewiring degron network	0.25
p.A393S	DO229028	LICA	ICGC	AATTT	DEG_SPOP_SBC_1	403:407	Mutation rewiring degron network	0.0556
p.K411R	SIDM00670	Pancreatic Carcinoma	GDSC	AATTT	DEG_SPOP_SBC_1	403:407	Mutation substituting flanking lysine	0.3333
p.K411R	ACH-000270	Pancreatic Cancer	CCLE	AATTT	DEG_SPOP_SBC_1	403:407	Mutation substituting flanking lysine	0.3333
p.K411R	ACH-001098	Pancreatic Cancer	CCLE	AATTT	DEG_SPOP_SBC_1	403:407	Mutation substituting flanking lysine	0.3333
p.K411R	HPAC	pancreas	COSMIC	AATTT	DEG_SPOP_SBC_1	403:407	Mutation substituting flanking lysine	0.3333

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*NOTE: the Kaplan plots were collected from OncoLnc