DegronMD - Q5RHP9(ERICH3)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V438G	SIDM01314	Colorectal Carcinoma	GDSC	IKENK	DEG_APCC_KENBOX_2	445:449	Mutation rewiring degron network	0.1389
p.T579P	SIDM02010	Esophageal Carcinoma	GDSC	ASSTS	DEG_SPOP_SBC_1	580:584	Mutation rewiring degron network	0.3056
p.S581L	SIDM00672	Hepatocellular Carcinoma	GDSC	ASSTS	DEG_SPOP_SBC_1	580:584	Mutation altering degron motif	0.6556
p.S581L	SIDM00660	Colorectal Carcinoma	GDSC	ASSTS	DEG_SPOP_SBC_1	580:584	Mutation altering degron motif	0.6556
p.S581L	SIDM00721	Small Cell Lung Carcinoma	GDSC	ASSTS	DEG_SPOP_SBC_1	580:584	Mutation altering degron motif	0.6556
p.A458V	SIDM00845	Burkitt's Lymphoma	GDSC	IKENK	DEG_APCC_KENBOX_2	445:449	Mutation rewiring degron network	0.0833
p.A458V	Daudi	haematopoietic and lymphoid tissue	COSMIC	IKENK	DEG_APCC_KENBOX_2	445:449	Mutation rewiring degron network	0.0833
p.S585F	SIDM01175	Other Sarcomas	GDSC	ASSTS	DEG_SPOP_SBC_1	580:584	Mutation rewiring degron network	0.3056
p.S585F	SW684	soft tissue	COSMIC	ASSTS	DEG_SPOP_SBC_1	580:584	Mutation rewiring degron network	0.3056
p.H588N	SIDM00953	Small Cell Lung Carcinoma	GDSC	ASSTS	DEG_SPOP_SBC_1	580:584	Mutation rewiring degron network	0.2222
p.H588N	CPC-N	lung	COSMIC	ASSTS	DEG_SPOP_SBC_1	580:584	Mutation rewiring degron network	0.2222
p.R442I	SIDM00193	Colorectal Carcinoma	GDSC	IKENK	DEG_APCC_KENBOX_2	445:449	Mutation rewiring degron network	0.25
p.R442I	SNU-81	large intestine	COSMIC	IKENK	DEG_APCC_KENBOX_2	445:449	Mutation rewiring degron network	0.25
p.V452L	SIDM00292	Small Cell Lung Carcinoma	GDSC	IKENK	DEG_APCC_KENBOX_2	445:449	Mutation rewiring degron network	0.25
p.V452L	LU-165	lung	COSMIC	IKENK	DEG_APCC_KENBOX_2	445:449	Mutation rewiring degron network	0.25
p.S584A	SIDM01470	Acute Myeloid Leukemia	GDSC	ASSTS	DEG_SPOP_SBC_1	580:584	Mutation altering degron motif	0.7588

Kaplan plot for ERICH3 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ERICH3

UniProt ID: Q5RHP9

Entrez ID: 127254

Protein name: Glutamate-rich protein 3

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for ERICH3 in