DegronMD - Q5SQQ9(VAX1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L281R	TCGA-L5-A43E	ESCA	TCGA	SLFSLPVPSL	DEG_COP1_1	271:280	Mutation rewiring degron network	0.3056
p.R287S	TCGA-OR-A5KB	ACC	TCGA	SLFSLPVPSL	DEG_COP1_1	271:280	Mutation rewiring degron network	0.1389
p.S283A	DO50349	ESAD	ICGC	SLFSLPVPSL	DEG_COP1_1	271:280	Mutation rewiring degron network	0.25
p.P266L	DO233749	GACA	ICGC	SLFSLPVPSL	DEG_COP1_1	271:280	Mutation rewiring degron network	0.1944
p.L272I	DO229028	LICA	ICGC	SLFSLPVPSL	DEG_COP1_1	271:280	Mutation altering degron motif	0.6063
p.A265S	SIDM02021	Esophageal Carcinoma	GDSC	SLFSLPVPSL	DEG_COP1_1	271:280	Mutation rewiring degron network	0.1667
p.A265T	SIDM00447	B-Lymphoblastic Leukemia	GDSC	SLFSLPVPSL	DEG_COP1_1	271:280	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons