DegronMD - Q5SZJ8(BEND6)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A223D	TCGA-A5-A0G1	UCEC	TCGA	AKSST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.1944
p.A223D	DO42472	UCEC	ICGC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.1944
p.E204K	TCGA-EE-A2MM	SKCM	TCGA	AKSST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.0556
p.E204K	DO222678	MELA	ICGC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.0556
p.E204K	DO37770	SKCM	ICGC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.0556
p.S216F	TCGA-FS-A1ZC	SKCM	TCGA	AKSST	DEG_SPOP_SBC_1	214:218	Mutation altering degron motif	0.7982
p.S216F	DO37487	SKCM	ICGC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation altering degron motif	0.7982
p.A214T	TCGA-G9-6364	PRAD	TCGA	AKSST	DEG_SPOP_SBC_1	214:218	Mutation altering degron motif	0.7139
p.A214T	DO36240	PRAD	ICGC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation altering degron motif	0.7139
p.A207T	DO222404	BTCA	ICGC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.1389
p.A214S	DO229019	LICA	ICGC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation altering degron motif	0.7588
p.H209N	DO231174	LUSC	ICGC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.1944
p.S217F	DO222662	MELA	ICGC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation altering degron motif	0.7982
p.A207V	DO228138	PBCA	ICGC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.1389
p.A207V	SIDM01960	Colorectal Carcinoma	GDSC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.1389
p.P226S	SIDM00683	Prostate Carcinoma	GDSC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.1111
p.P226S	LNCaP-Clone-FGC	prostate	COSMIC	AKSST	DEG_SPOP_SBC_1	214:218	Mutation rewiring degron network	0.1111

Kaplan plot for BEND6 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

BEND6

UniProt ID: Q5SZJ8

Entrez ID: 221336

Protein name: BEN domain-containing protein 6

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for BEND6 in