DegronMD - Q5T160(RARS2)

RARS2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R258H	TCGA-A5-A0VP	UCEC	TCGA	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation rewiring degron network	0.3056
p.R258H	TCGA-NH-A5IV	COAD	TCGA	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation rewiring degron network	0.3056
p.R258H	DO49095	COAD	ICGC	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation rewiring degron network	0.3056
p.R258H	DO42600	UCEC	ICGC	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation rewiring degron network	0.3056
p.S270T	TCGA-EI-6882	READ	TCGA	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation rewiring degron network	0.1667
p.S270T	DO36531	READ	ICGC	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation rewiring degron network	0.1667
p.R273H	TCGA-EO-A22R	UCEC	TCGA	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation rewiring degron network	0.0833
p.R273H	DO42713	UCEC	ICGC	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation rewiring degron network	0.0833
p.G260R	SIDM02072	Colorectal Carcinoma	GDSC	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation altering degron motif	0.6457
p.R254W	SIDM00118	Colorectal Carcinoma	GDSC	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation rewiring degron network	0.1944
p.R254W	ACH-001081	Colon/Colorectal Cancer	CCLE	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation rewiring degron network	0.1944
p.R254W	HCC2998	large intestine	COSMIC	LGVYFD	LIG_APCC_ABBA_1	259:264	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc