DegronMD - Q5T2E6(ARMH3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T343S	SIDM01030	Esophageal Squamous Cell Carcinoma	GDSC	PVTPLGT	DEG_SCF_FBW7_1	337:343	Mutation altering degron motif	0.6005
p.T343S	KYSE-180	oesophagus	COSMIC	PVTPLGT	DEG_SCF_FBW7_1	337:343	Mutation altering degron motif	0.6005
p.P345L	SIDM01168	Colorectal Carcinoma	GDSC	PVTPLGT	DEG_SCF_FBW7_1	337:343	Mutation rewiring degron network	0.2778
p.P345L	SIDM00941	Kidney Carcinoma	GDSC	PVTPLGT	DEG_SCF_FBW7_1	337:343	Mutation rewiring degron network	0.2778
p.P345L	SIDM00382	Glioblastoma	GDSC	PVTPLGT	DEG_SCF_FBW7_1	337:343	Mutation rewiring degron network	0.2778
p.P345L	SIDM00462	Acute Myeloid Leukemia	GDSC	PVTPLGT	DEG_SCF_FBW7_1	337:343	Mutation rewiring degron network	0.2778
p.P345L	SIDM00727	Non-Small Cell Lung Carcinoma	GDSC	PVTPLGT	DEG_SCF_FBW7_1	337:343	Mutation rewiring degron network	0.2778
p.P345L	SIDM01517	Head and Neck Carcinoma	GDSC	PVTPLGT	DEG_SCF_FBW7_1	337:343	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons