DegronMD - Q5T7B8(KIF24)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.I58M	TCGA-BH-A18V	BRCA	TCGA	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.6507
p.I58M	DO4743	BRCA	ICGC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.6507
p.D50E	DO229003	COCA	ICGC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.5647
p.D50E	DO229505	LAML	ICGC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.5647
p.D50E	DO225404	LAML	ICGC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.5647
p.D50E	DO229047	LICA	ICGC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.5647
p.R51H	DO51474	PACA	ICGC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.8244
p.R51H	SIDM01943	Colorectal Carcinoma	GDSC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.8244
p.R53C	SIDM02039	Colorectal Carcinoma	GDSC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.719
p.R51C	SIDM00845	Burkitt's Lymphoma	GDSC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.8301
p.R51C	SIDM00654	Small Cell Lung Carcinoma	GDSC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.8301
p.R51C	SIDM00650	Small Cell Lung Carcinoma	GDSC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.8301
p.R51C	SIDM00971	Breast Carcinoma	GDSC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.8301
p.R51C	SIDM00493	Other Solid Cancers	GDSC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.8301
p.R51C	SIDM01681	Non-Cancerous	GDSC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.8301
p.I58V	SIDM00453	Pancreatic Carcinoma	GDSC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.5965
p.I58V	PA-TU-8988T	pancreas	COSMIC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.5965
p.L43V	SIDM01397	Melanoma	GDSC	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation rewiring degron network	0.1389
p.L43V	ACH-000765	Skin Cancer	CCLE	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation rewiring degron network	0.1389
p.I58T	ACH-001484	Leukemia	CCLE	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.5966
p.I58T	ACH-001485	Leukemia	CCLE	DRKRLFQLI	DEG_APCC_DBOX_1	50:58	Mutation altering degron motif	0.5966

Kaplan plot for KIF24 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

KIF24

UniProt ID: Q5T7B8

Entrez ID: 347240

Protein name: Kinesin-like protein KIF24

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for KIF24 in