DegronMD - Q5T7N8(FAM27D1)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G173E	DO228941	LICA	ICGC	LTPTNT	DEG_SCF_FBW7_1	183:188	Mutation rewiring degron network	0.0556
p.G173E	DO229006	LICA	ICGC	LTPTNT	DEG_SCF_FBW7_1	183:188	Mutation rewiring degron network	0.0556
p.R182L	DO228945	LICA	ICGC	LTPTNT	DEG_SCF_FBW7_1	183:188	Mutation rewiring degron network	0.3056
p.R182L	DO229058	LICA	ICGC	LTPTNT	DEG_SCF_FBW7_1	183:188	Mutation rewiring degron network	0.3056
p.S189F	DO228947	LICA	ICGC	LTPTNT	DEG_SCF_FBW7_1	183:188	Mutation rewiring degron network	0.3056
p.P196S	DO228950	LICA	ICGC	LTPTNT	DEG_SCF_FBW7_1	183:188	Mutation rewiring degron network	0.1111
p.P196S	DO228960	LICA	ICGC	LTPTNT	DEG_SCF_FBW7_1	183:188	Mutation rewiring degron network	0.1111
p.P196S	DO229056	LICA	ICGC	LTPTNT	DEG_SCF_FBW7_1	183:188	Mutation rewiring degron network	0.1111
p.P196S	DO229057	LICA	ICGC	LTPTNT	DEG_SCF_FBW7_1	183:188	Mutation rewiring degron network	0.1111
p.P194S	DO229058	LICA	ICGC	LTPTNT	DEG_SCF_FBW7_1	183:188	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons