DegronMD - Q5TAT6(COL13A1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G208A	TCGA-62-8395	LUAD	TCGA	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.0556
p.G208A	DO45368	LUAD	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.0556
p.K210N	TCGA-AA-A010	COAD	TCGA	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation substituting flanking lysine	0.2222
p.M225I	TCGA-AX-A0J1	UCEC	TCGA	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6507
p.M225I	DO41199	UCEC	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6507
p.S224R	TCGA-BR-8680	STAD	TCGA	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6316
p.S224R	DO47769	STAD	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6316
p.S223R	TCGA-BR-A4PF	STAD	TCGA	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6316
p.S223R	DO38268	STAD	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6316
p.P226S	TCGA-D1-A103	UCEC	TCGA	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.5641
p.P226S	DO231149	LUSC	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.5641
p.P226S	DO42312	UCEC	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.5641
p.G208E	TCGA-D3-A2JH	SKCM	TCGA	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.0556
p.G208E	TCGA-EE-A3JD	SKCM	TCGA	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.0556
p.G208E	DO47263	SKCM	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.0556
p.G208E	DO50299	SKCM	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.0556
p.G211V	DO233634	GACA	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.1389
p.V234F	DO229018	LICA	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.1111
p.P218S	DO222498	MELA	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6752
p.A230S	DO220314	SARC	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.2222
p.E220K	DO229453	SKCA	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.591
p.P221H	DO42568	UCEC	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.7694
p.P217S	DO41331	UCEC	ICGC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.3056
p.S210G	NCI-H838	lung	COSMIC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation substituting flanking lysine	0.2222
p.P212T	DU-145	prostate	COSMIC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.1667
p.Q212L	HT55	large intestine	COSMIC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.1667
p.V236L	NCI-H1155	lung	COSMIC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.0556
p.P230S	SNU-C2B	large intestine	COSMIC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.2222
p.V227L	NCI-H1155	lung	COSMIC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.3056
p.S216G	NCI-H838	lung	COSMIC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.2778
p.S213N	NCI-H1435	lung	COSMIC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.1944
p.P233S	SNU-C2B	large intestine	COSMIC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.1389
p.P233T	NCI-H727	lung	COSMIC	HRECLSSMP	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.1389

Kaplan plot for COL13A1 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

COL13A1

UniProt ID: Q5TAT6

Entrez ID: 1305

Protein name: Collagen alpha-1(XIII) chain (COLXIIIA1)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for COL13A1 in