DegronMD - Q5TH69(ARFGEF3)

ARFGEF3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S291L	SIDM00860	Head and Neck Carcinoma	GDSC	AHTSS	DEG_SPOP_SBC_1	280:284	Mutation rewiring degron network	0.1389
p.S291L	FADU	upper aerodigestive tract	COSMIC	AHTSS	DEG_SPOP_SBC_1	280:284	Mutation rewiring degron network	0.1389
p.P271S	SIDM00719	Small Cell Lung Carcinoma	GDSC	AHTSS	DEG_SPOP_SBC_1	280:284	Mutation rewiring degron network	0.0833
p.P271S	NCI-H345	lung	COSMIC	AHTSS	DEG_SPOP_SBC_1	280:284	Mutation rewiring degron network	0.0833
p.D274E	SIDM00094	Kidney Carcinoma	GDSC	AHTSS	DEG_SPOP_SBC_1	280:284	Mutation rewiring degron network	0.1667
p.D274E	SN12C	kidney	COSMIC	AHTSS	DEG_SPOP_SBC_1	280:284	Mutation rewiring degron network	0.1667
p.T276S	SIDM00168	Head and Neck Carcinoma	GDSC	AHTSS	DEG_SPOP_SBC_1	280:284	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc