DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
NUTM2D
UniProt ID:
Q5VT03
Entrez ID:
Protein name:
NUT family member 2D
External links:
UniprotKB
HGNC
RefSeq
COSMIC
Please click
HERE
for better display.
Functional annotation
Mutations
Degrons
Degron mutations
Network-rewiring
Drug response
Drug resistance
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GO - Biological processes (BP):
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GO - Molecular function (MF):
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GO - Cellular component (CC):
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Choose a PDB ID:
Open in full screen with detailed sequence annotations
NUTM2D
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AAchange
Cancer
Sample
Mutation type
Dataset
Degron hit
Class
E3 ligase
Source protein
Location
Detail
Mutation
Sample
Cancer
Degron hit
Class
Location
Dataset
Mutation
Sample
Cancer
Dataset
Degron hit
Class
Location
Type
Impact score
p.G102C
TCGA-09-2044
OV
TCGA
PSTPLVT
DEG_SCF_FBW7_1
110:116
Mutation rewiring degron network
0.1111
p.G102C
DO28923
OV
ICGC
PSTPLVT
DEG_SCF_FBW7_1
110:116
Mutation rewiring degron network
0.1111
Cell ID
Cell name
Cancer
Drug
IC50(uM)
Dataset
Protein
Degron
Cancer code
Cancer type
Drug
AVG_IC50(uM)(mutated)
AVG_IC50(uM)(Non-mutated)
Details
Kaplan plot for NUTM2D in
Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from
OncoLnc