DegronMD - Q5VYJ5(MALRD1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E1045V	TCGA-AY-A69D	COAD	TCGA	LPTPPET	DEG_SCF_FBW7_1	1033:1039	Mutation rewiring degron network	0.1667
p.P1026T	SIDM00967	Ovarian Carcinoma	GDSC	LPTPPET	DEG_SCF_FBW7_1	1033:1039	Mutation rewiring degron network	0.1389
p.P1026T	SIDM00454	Rhabdomyosarcoma	GDSC	LPTPPET	DEG_SCF_FBW7_1	1033:1039	Mutation rewiring degron network	0.1389
p.P1026T	SIDM00656	Burkitt's Lymphoma	GDSC	LPTPPET	DEG_SCF_FBW7_1	1033:1039	Mutation rewiring degron network	0.1389
p.P1026T	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	LPTPPET	DEG_SCF_FBW7_1	1033:1039	Mutation rewiring degron network	0.1389
p.P1026T	SIDM00431	T-Lymphoblastic Leukemia	GDSC	LPTPPET	DEG_SCF_FBW7_1	1033:1039	Mutation rewiring degron network	0.1389
p.L1029F	SIDM00299	Other Sarcomas	GDSC	LPTPPET	DEG_SCF_FBW7_1	1033:1039	Mutation rewiring degron network	0.2222
p.L1029F	MFH-ino	soft tissue	COSMIC	LPTPPET	DEG_SCF_FBW7_1	1033:1039	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons