DegronMD - Q5VZQ5(TEX36)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R46Q	TCGA-2W-A8YY	CESC	TCGA	PPIY	ITCH	53:56	Mutation rewiring degron network	0.1389
p.R46Q	TCGA-L5-A8NW	ESCA	TCGA	PPIY	ITCH	53:56	Mutation rewiring degron network	0.1389
p.R46Q	DO223732	CESC	ICGC	PPIY	ITCH	53:56	Mutation rewiring degron network	0.1389
p.L44V	DO234187	ESAD	ICGC	PPIY	ITCH	53:56	Mutation rewiring degron network	0.0833
p.Y56C	DO48222	ESCA	ICGC	PPIY	ITCH	53:56	Mutation altering degron motif	0.7087
p.H43Q	DO229037	LICA	ICGC	PPIY	ITCH	53:56	Mutation rewiring degron network	0.0556
p.A48V	DO44862	LICA	ICGC	PPIY	ITCH	53:56	Mutation rewiring degron network	0.1944
p.A48V	SIDM00217	Colorectal Carcinoma	GDSC	PPIY	ITCH	53:56	Mutation rewiring degron network	0.1944
p.A48V	ACH-000999	Colon/Colorectal Cancer	CCLE	PPIY	ITCH	53:56	Mutation rewiring degron network	0.1944
p.A48V	SNU-1040	large intestine	COSMIC	PPIY	ITCH	53:56	Mutation rewiring degron network	0.1944
p.R59W	DO32829	PACA	ICGC	PPIY	ITCH	53:56	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons