DegronMD - Q5VZR2(NUTM2G)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V170M	TCGA-2W-A8YY	CESC	TCGA	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.3056
p.V170M	TCGA-FR-A726	SKCM	TCGA	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.3056
p.V170M	DO223732	CESC	ICGC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.3056
p.V170M	DO48665	SKCM	ICGC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.3056
p.V170M	SIDM00621	Ewing's Sarcoma	GDSC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.3056
p.V170M	ACH-002113	Bone Cancer	CCLE	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.3056
p.V170M	EW-13	bone	COSMIC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.3056
p.P168H	TCGA-85-8355	LUSC	TCGA	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation altering degron motif	0.7694
p.P168H	DO45488	LUSC	ICGC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation altering degron motif	0.7694
p.N174K	TCGA-L9-A5IP	LUAD	TCGA	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.1944
p.N174K	DO49873	LUAD	ICGC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.1944
p.A175T	DO233884	GACA	ICGC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.1667
p.P172S	DO231049	LUSC	ICGC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.25
p.P177L	DO27779	MALY	ICGC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.1111
p.W178C	DO229224	THCA	ICGC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.0833
p.N174Y	DO229100	UTCA	ICGC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.1944
p.P172L	SIDM01112	Osteosarcoma	GDSC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.25
p.P172L	SJSA-1	bone	COSMIC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.25
p.S171F	SIDM00516	Melanoma	GDSC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.2778
p.S171F	ACH-002166	Skin Cancer	CCLE	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.2778
p.S171F	MZ7-mel	skin	COSMIC	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.2778
p.G154V	ACH-000953	Leukemia	CCLE	PPAAQVAPI	DEG_SIAH_1	161:169	Mutation rewiring degron network	0.1389

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NUTM2G

UniProt ID: Q5VZR2

Entrez ID: 441457

Protein name: NUT family member 2G

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NUTM2G in