DegronMD - Q5XKE5(KRT79)

KRT79

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T530M	TCGA-78-8660	LUAD	TCGA	VKTSS	DEG_SPOP_SBC_1	528:532	Mutation altering degron motif	0.7423
p.T530M	DO222389	BTCA	ICGC	VKTSS	DEG_SPOP_SBC_1	528:532	Mutation altering degron motif	0.7423
p.T530M	DO45321	LUAD	ICGC	VKTSS	DEG_SPOP_SBC_1	528:532	Mutation altering degron motif	0.7423
p.L522M	TCGA-A4-7583	KIRP	TCGA	VKTSS	DEG_SPOP_SBC_1	528:532	Mutation rewiring degron network	0.1667
p.L522M	DO20870	KIRP	ICGC	VKTSS	DEG_SPOP_SBC_1	528:532	Mutation rewiring degron network	0.1667
p.K524N	DO42673	UCEC	ICGC	VKTSS	DEG_SPOP_SBC_1	528:532	Mutation substituting flanking lysine	0.3333
p.T527M	SIDM00633	Breast Carcinoma	GDSC	VKTSS	DEG_SPOP_SBC_1	528:532	Mutation blocking phosphorylation signal	0.75
p.T527M	SIDM00483	Esophageal Carcinoma	GDSC	VKTSS	DEG_SPOP_SBC_1	528:532	Mutation blocking phosphorylation signal	0.75
p.T527M	SIDM01133	Other Solid Cancers	GDSC	VKTSS	DEG_SPOP_SBC_1	528:532	Mutation blocking phosphorylation signal	0.75
p.T527M	SIDM00785	Acute Myeloid Leukemia	GDSC	VKTSS	DEG_SPOP_SBC_1	528:532	Mutation blocking phosphorylation signal	0.75

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*NOTE: the Kaplan plots were collected from OncoLnc