DegronMD - Q5XUX0(FBXO31)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L70M	DO229191	THCA	ICGC	PRCSLLELP	DEG_APCC_DBOX_1	63:71	Mutation altering degron motif	0.5999
p.G57D	DO229259	THCA	ICGC	PRCSLLELP	DEG_APCC_DBOX_1	63:71	Mutation rewiring degron network	0.1667
p.L75P	DO229201	THCA	ICGC	PRCSLLELP	DEG_APCC_DBOX_1	63:71	Mutation rewiring degron network	0.2222
p.V76L	DO229095	THCA	ICGC	PRCSLLELP	DEG_APCC_DBOX_1	63:71	Mutation rewiring degron network	0.1944
p.P58T	ACH-000948	Gastric Cancer	CCLE	PRCSLLELP	DEG_APCC_DBOX_1	63:71	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons