DegronMD

Uniprot ID: Q5XUX0

Source protein: F-box only protein 31

Source gene: FBXO31

Class: DEG_APCC_DBOX_1

Location: 63:71

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9153

ASA_SCORE: 60.7556

COIL: 0.6847

CONS_SCORE: 0.4611

DSS_SCORE: 0.3655

HELIX: 0.287

FCONS_SCORE: 1.0788

RIG_SCORE: 0.7538

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.L70M	DO229191	THCA	ICGC	PRCSLLELP	DEG_APCC_DBOX_1	0.5999
p.G57D	DO229259	THCA	ICGC	PRCSLLELP	DEG_APCC_DBOX_1	0.1667
p.L75P	DO229201	THCA	ICGC	PRCSLLELP	DEG_APCC_DBOX_1	0.2222
p.V76L	DO229095	THCA	ICGC	PRCSLLELP	DEG_APCC_DBOX_1	0.1944
p.P58T	ACH-000948	Gastric Cancer	CCLE	PRCSLLELP	DEG_APCC_DBOX_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q5XUX0	F-box only protein 31	DEG_APCC_DBOX_1	63:71	PRCSLLELP	APC,CDC20,FZR1	0.9153	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons