DegronMD - Q5XUX1(FBXW9)

FBXW9

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R66W	TCGA-CJ-5686	KIRC	TCGA	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation rewiring degron network	0.1389
p.G44W	TCGA-HR-A2OG	SKCM	TCGA	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation rewiring degron network	0.0833
p.A58T	DO233676	GACA	ICGC	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation altering degron motif	0.6028
p.H57Q	DO228986	LICA	ICGC	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation altering degron motif	0.7582
p.H65Q	DO229031	LICA	ICGC	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation rewiring degron network	0.1667
p.A58E	DO229045	LICA	ICGC	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation altering degron motif	0.659
p.R56W	DO38711	STAD	ICGC	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation altering degron motif	0.8634
p.D64N	DO229250	THCA	ICGC	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation rewiring degron network	0.1944
p.R49H	SIDM01016	T-Lymphoblastic Leukemia	GDSC	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation rewiring degron network	0.2222
p.R49H	SIDM01263	T-Lymphoblastic Leukemia	GDSC	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation rewiring degron network	0.2222
p.R49H	ACH-000995	Leukemia	CCLE	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation rewiring degron network	0.2222
p.R49H	Jurkat	haematopoietic and lymphoid tissue	COSMIC	LSTPAAS	DEG_SCF_FBW7_1	53:59	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc