DegronMD - Q5XXA6(ANO1)

ANO1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R15C	TCGA-15-0742	GBM	TCGA	NEKYSTLP	CBL_PTK	4:11	Mutation rewiring degron network	0.2222
p.R15C	DO13623	GBM	ICGC	NEKYSTLP	CBL_PTK	4:11	Mutation rewiring degron network	0.2222
p.P11T	TCGA-FS-A1ZA	SKCM	TCGA	NEKYSTLP	CBL_PTK	4:11	Mutation altering degron motif	0.7031
p.P11T	DO37551	SKCM	ICGC	NEKYSTLP	CBL_PTK	4:11	Mutation altering degron motif	0.7031
p.S8L	DO231583	LINC	ICGC	NEKYSTLP	CBL_PTK	4:11	Mutation altering degron motif	0.8778
p.D14G	SIDM01045	Endometrial Carcinoma	GDSC	NEKYSTLP	CBL_PTK	4:11	Mutation rewiring degron network	0.25
p.D14G	ACH-000978	Endometrial/Uterine Cancer	CCLE	NEKYSTLP	CBL_PTK	4:11	Mutation rewiring degron network	0.25
p.D14G	EN	endometrium	COSMIC	NEKYSTLP	CBL_PTK	4:11	Mutation rewiring degron network	0.25
p.Y16N	NCI-H1651	lung	COSMIC	NEKYSTLP	CBL_PTK	4:11	Mutation rewiring degron network	0.1944
p.G10S	KARPAS-1106P	haematopoietic and lymphoid tissue	COSMIC	NEKYSTLP	CBL_PTK	4:11	Mutation altering degron motif	0.6993
p.P17L	HCC1395	breast	COSMIC	NEKYSTLP	CBL_PTK	4:11	Mutation rewiring degron network	0.1667
p.A13V	NCI-H630	large intestine	COSMIC	NEKYSTLP	CBL_PTK	4:11	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc