DegronMD - Q674R7(ATG9B)

ATG9B

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S137C	TCGA-CM-6168	COAD	TCGA	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation rewiring degron network	0.1389
p.S137C	DO9602	COAD	ICGC	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation rewiring degron network	0.1389
p.S130T	DO228924	LICA	ICGC	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation altering degron motif	0.6005
p.P134H	DO50911	LICA	ICGC	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation rewiring degron network	0.2222
p.D136Y	DO23270	LINC	ICGC	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation rewiring degron network	0.1667
p.Q135H	DO23270	LINC	ICGC	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation rewiring degron network	0.1944
p.G115R	DO229227	THCA	ICGC	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation rewiring degron network	0.0833
p.P124L	DO42304	UCEC	ICGC	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation altering degron motif	0.6471
p.P120Q	SIDM00320	Non-Small Cell Lung Carcinoma	GDSC	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation rewiring degron network	0.2222
p.P120Q	VMRC-LCD	lung	COSMIC	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation rewiring degron network	0.2222
p.T119A	SIDM00988	Kidney Carcinoma	GDSC	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation rewiring degron network	0.1944
p.T119A	ACH-000792	Kidney Cancer	CCLE	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation rewiring degron network	0.1944
p.T119A	BFTC-909	kidney	COSMIC	PATPTPS	DEG_SCF_FBW7_1	124:130	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc