DegronMD - Q68CZ1(RPGRIP1L)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E1032Q	TCGA-4Z-AA80	BLCA	TCGA	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.6744
p.E1032Q	DO218986	BLCA	ICGC	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.6744
p.E1035D	TCGA-66-2773	LUSC	TCGA	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.3056
p.E1035D	DO26536	LUSC	ICGC	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.3056
p.E1032K	TCGA-VS-A9UZ	CESC	TCGA	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.7022
p.E1032K	DO51646	CESC	ICGC	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.7022
p.G1025S	DO229016	COCA	ICGC	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.1944
p.G1025S	DO229489	LAML	ICGC	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.1944
p.G1025S	DO229505	LAML	ICGC	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.1944
p.G1025S	DO228947	LICA	ICGC	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.1944
p.G1025S	DO229047	LICA	ICGC	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.1944
p.Q1038K	DO229029	LICA	ICGC	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.2222
p.T1034A	SIDM01146	Gastric Carcinoma	GDSC	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.6028
p.T1034A	NCI-SNU-1	stomach	COSMIC	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.6028
p.S1026F	ACH-001536	Bile Duct Cancer	CCLE	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation rewiring degron network	0.2222
p.E1034G	ACH-001838	Bile Duct Cancer	CCLE	VKENT	DEG_APCC_KENBOX_2	1030:1034	Mutation altering degron motif	0.7199

Kaplan plot for RPGRIP1L in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RPGRIP1L

UniProt ID: Q68CZ1

Entrez ID: 23322

Protein name: Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RPGRIP1L in